edisan.fr). Edisan® is a commercially available software updated every 6 weeks, used to help physicians for travel advice in general TSA HDAC in vivo and for malaria prophylaxis and vaccine prescriptions in particular. Updated specific recommendations are provided for each country, and within each country for specific areas at risk. Physicians can also use folders with updated recommendations and prefilled prescriptions for malaria prophylaxis, mosquito repellents, and mosquito nets. During the visit,

patients receive individualized travel health advice according to their medical condition, and general advice on vector-borne diseases, water-borne diseases, animal bites, as well as sexually transmitted diseases, high altitude sickness, and trauma. Patients are prescribed vaccines and malaria chemoprophylaxis when appropriate. Finally, Ponatinib cell line they are encouraged to update their routine vaccination (hepatitis B, Diphtheria-Tetanus-Poliomyelitis, measles, and pertussis). Vaccinations are then performed by one of the three nurses in the center on the same day. The objective of the study was to assess the adequacy of malaria prophylaxis, yellow fever, and hepatitis A vaccination prescriptions to French recommendations. For

that purpose we used the questionnaires available in our center that were designed to assess our current practice and to ensure traceability of the advice and prescriptions

given to travelers. The questionnaire is first filled by the traveler while he/she is waiting for the physician and the Anidulafungin (LY303366) data are then checked and completed by the physician. The questionnaires covered the following areas: age, sex, medical condition and past medical history of each traveler, ongoing treatment, pregnancy status, and vaccine status. The trip characteristics are also recorded: destinations and itineraries, duration, and type of travel (rural or urban, for tourism or visiting friends and relatives, or professional). On the same questionnaire, the physician prescribes the vaccines to be administered by the nurse and treatments recommended during the visit (chemoprophylaxis for malaria, anti-diarrheal agents or antibiotics for travelers’ diarrhea or any other specific treatment). The reasons for the choice of malaria prophylaxis prescribed are also provided by the physician. The majority of questions could be answered by “yes” or “no,” some questions provided answer choices, and a few others allowed free text entries. All physicians were informed of the study goals and time lines of implementation. At the end of the study period, all questionnaires were reviewed by two investigators who assessed the adequacy of the prescriptions to the French recommendations for malaria chemoprophylaxis and yellow fever and hepatitis A vaccines.