For steady flows, the multizone model of flow between compartment

For steady flows, the multizone model of flow between compartments employs a semi-empirical closure model to relate the pressure drop with the average velocity through the holes. The approach

adopted here is consistent with other studies (see Chu et al., 2009, Mora Dapagliflozin mw et al., 2003 and Tan and Glicksman, 2005). The pressure difference between two neighbouring compartments [i1][j1][i1][j1] and [i2][j2][i2][j2] is equation(5) p[i1][j1]−p[i2][j2]=ξ[i1][j1],[i2][j2]ρ|f[i1][j1],[i2][j2]|f[i1][j1],[i2][j2]A[i1][j1],[i2][j2]2.Here ξ[i1][j1],[i2][j2]ξ[i1][j1],[i2][j2] is the local pressure loss coefficient between compartment [i1][j1][i1][j1] and [i2][j2][i2][j2], which is assumed to be constant. The pressure loss coefficient ξ is usually determined empirically. For instance, Talazoparib mouse for flow through a sharp-edged circle orifice (see Cao et al., 2011, Charles et al., 2005 and Chu et al., 2009) which is typical of the connection between compartments in ballast tanks, the pressure loss coefficient can be estimated by ( Chu et al., 2010) equation(6) ξ=2.58[1−exp(−60β)],ξ=2.58[1−exp(−60β)],where β is the ratio of the cross-sectional area of the orifice to the cross-sectional area of the partition wall. The fluid is transported

by the mean flow and mixed by turbulent dispersion. The mean flow is largest in the passage between compartments and is smallest within compartments. Integrating the flushed fraction over compartment [i][j][i][j], we Tacrolimus (FK506) have an approximate model describing the variation of the flushed fraction with time, i.e. equation(7) V[i][j]dC[i][j]dt=∑f[i][j],inC[i][j],in−∑f[i][j],outC[i][j],where C[i][j],inC[i][j],in

is the flushed fraction in the compartment(s) flowing into compartment [i][j]. The general multizone model that consists of (4), (5) and (7) for an m×n tank is described in more detail in Appendix A. The mathematical model generates a time series for the flushed fraction of water in each compartment. A set of diagnostic tools are required to quantify the timescale when each compartment is flushed and the rate at which they are flushed by the incoming water. The dimensionless characteristic time T1/2,[i][j]T1/2,[i][j] for flushing is identified when half of the original fluid in compartment [i  ][j  ] has been flushed out, mentioned as ‘half flushed time’ equation(8) T1/2,[i][j]=T|C[i][j]=1/2,T1/2,[i][j]=T|C[i][j]=1/2,and α1/2,[i][j]α1/2,[i][j] represents the characteristic flushing rate, at which compartment [i  ][j  ] is being flushed when half of its original fluid has been flushed out (that is, when T=T1/2,[i][j]T=T1/2,[i][j]) equation(9) α1/2,[i][j]=V[i][j]VdC[i][j]dT|T=T1/2,[i][j]. The flushing efficiency C¯, is defined as the fraction of the original fluid that has been flushed out of the whole tank, i.e. equation(10) C¯(T)=∑i∑jC[i][j]V[i][j]∑i∑jV[i][j].

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