J. Nutr. 139: 1833-1838, 2009.”
“More MK-8931 molecular weight than 200 people in China suffered illness with symptoms of diarrhetic shellfish poisoning (DSP) following consumption of mussels (Mytilus galloprovincialis). The event occurred in the cities of Ningbo and Ningde near the East China Sea in May, 2011. LC-MS/MS analysis showed that high concentrations of okadaic acid, dinophysistoxin-1, and their acyl esters were responsible for the incidents. The total concentration was more than 40 times the EU regulatory limit of 160 mu g OA eq./kg. Pectentoxin-2 and its seco-acids were also present in the mussels. Additionally, yessotoxins were found to be responsible for positive
mouse bioassay results on scallop (Patinopecten yessoensis) and oyster (Crassostrea talienwhanensis) samples collected from the North Yellow Sea in June, 2010. This work shows that high levels of lipophilic toxins BMS202 in vivo can accumulate in shellfish from the Chinese coast and it emphasises that adequate chemical analytical methodologies are needed for monitoring purposes. Further research is required to broaden the knowledge on the occurrence of lipophilic toxins in
Chinese shellfish. (C) 2012 Elsevier Ltd. All rights reserved.”
“A novel and sensitive anion receptor 3, bearing Schiff base structure, nitrophenyl azobenzol and carboxyl groups, was developed and characterized as a single chemosensor for the recognition of HSO4- anion. The different responses of UV-vis spectra and color changes of 3 could be applied to the recognition for HSO4- over other anions such as F-, Cl-, Br-, I-, AcO-, H2PO4- and CIO4- by the naked eye. Furthermore, the anion binding interaction of receptor-anion was also studied using UV-vis and H-1 NMR titration which revealed that 3 displayed a remarkable binding ability for the HSO4- with an association constant K-a = 6.59 x 10(4) M-1. And the detection limitation of HSO4- with the receptor 3 was 2.0
x 10(-6) mol L-1 in aqueous solution. Most importantly, the qualitative detection of HSO4- using receptor 3 was attempted with test kit which was made from receptor 3. Crown Copyright (C) 2012 Published by Elsevier B.V. All rights reserved.”
“BACKGROUND Frequent idiopathic premature ventricular complexes (PVCs) can result in a reversible form of cardiomyopathy. In this study, the determinants of PVC-induced left MX69 mouse ventricular (LV) dysfunction were assessed.\n\nMETHODS The subjects of this study were 241 consecutive patients (115 men [48%], mean age 48 +/- 14 years) referred for ablation of frequent PVCs. One hundred eighty patients (75%) experienced palpitations and 61 (25%) did not. The PVC burden was determined by 24-hour Holter monitoring, and echocardiograms were performed to assess LV function. An LV ejection fraction of <50% was considered abnormal.\n\nRESULTS LV ejection fraction (mean 0.36 +/- 0.09) was present in 76 of 241 patients (32%).