The aetiology of the underlying liver disease was: HBV (41%), Hepatitis C (23%), and Alcohol related liver disease (16%). The median age at diagnosis was 56 years, 62% were male. The median duration

of surveillance was 3.4 years. HCC was detected in 23 patients (5%). The overall adherence rate for AFP testing and US surveillance was 79% and 59%, respectively. US adherence correlated strongly with clinic attendance but even in those attending regularly, 20% of US surveillance scans were missed. Conclusion: The poor performance of US surveillance highlights the rationale for continuing AFP testing at this time. Strategies that we have undertaken to improve US surveillance rates include: a patient education brochure, nurse specialist cirrhosis clinics, and improving clinic non-attendance procedures. Key Word(s): 1. HCC; 2. ultrasound; 3. cirrhosis; 4. Surveillance; Presenting buy LEE011 Author: JIN TAO Additional Authors: LEIJIA LI, BIN WU Corresponding Author: JIN TAO Affiliations: The Third Affiliated Hospital of Sun Yat-Sen University Objective: To investigate the clinical characteristics of spontaneous bacterial peritonitis (SBP)

associated with cirrhosis to provide basis for the clinical reasonable application. Methods: The clinical manifestations and signs, the laboratory examinations, ascitic fluid cultures and drugs sensitivity test and the prognosis of SBP were retrospectively analyzed in 82 patients with cirrhosis. Results: Among the 82 patients, the ascites bacterial culture was positive in 28 cases, the Gram-negative bacilli covered the largest percentage of pathogenic bacteria (23 cases, 82.1 %). Among them, PS-341 in vivo MycoClean Mycoplasma Removal Kit the Escherichia coli was the most common of all (15 cases, 53.6 %). Conclusion: Patiens with liver cirrhosis of unknown cause fever, abdominal pain, rapid increase in short-term ascites or peripheral blood leukocytes, neutrophils should be alert to the occurrence of SBP. The early diagnosis of spontaneous peritonitis and the prompt, sufficiency and effective antibiotic treatment are the primary factors to improve the later period liver disease patient

prognosis. Key Word(s): 1. peritonitis; 2. cirrhosis; 3. ascites; Presenting Author: JIN TAO Additional Authors: YINGHUI YANG, BIN WU Corresponding Author: JIN TAO Affiliations: The Third Affiliated Hospital of Sun Yat-Sen University Objective: To compare the epidemiological, clinical, biological and histological characters among autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and their overlap syndrome (OS), and to assess the value of IgM and IgG in differentiating AIH, PBC and OS. Methods: One hundred and six cases in our hospital from July of 2006 to July of 2010 were analyzed. The clinical manifestations and signs, the laboratory examinations were analyzed We evaluated the expression of IgM and IgG cells in liver tissues by immunostaining, and their titer in serum by ELISA.