The aim of this study was to determine the prevalence of reflux esophagitis and Helicobacter pylori infection and their relationship in young healthy Japanese volunteers, medical students. Methods: Upper gastrointestinal endoscopy was performed in 550 young healthy Japanese medical school students Fostamatinib mouse (age range 21–36 years, mean 23.4 years) between 2008 and 2013. Upper gastric clinical symptoms were monitored with questionnaires of FSSG scales. Helicobacter pylori infection was determined by detecting urinary

IgG antibodies. Upper gastric clinical symptoms were monitored with questionnaires of FSSG scales. Results: Helicobacter pylori antibodies were detected in 50 of the 550 subjects (9.09%) with endoscopic chronic gastritis without peptic ulcers. Endoscopic selleck chemicals llc reflux esophagitis was detected in 55 out of the 550 subjects (10%), including grade A in 48 subjects (8.7%), grade B in 6 (1.09%) and grade C in 1 (0.18%). Only 5 subject with reflux esophagitis was Helicobacter pylori-positive, and the

other 50 subjects with esophagitis were Helicobacter pylori-negative. Infection rate of Helicobacter pylori decreased around 40% during the last 6 years in a time dependent manner, although relatively high prevalence of reflux esophagitis of 10% was not changed during the last 6 year. Several factors were related to the prevalence of reflux esophagitis and most critical risk factors were lifestyles including alcohol consumption and increase in body weight. Clinical symptoms of heartburn were more common and FSSG scales were high in subjects

with reflux esophagitis. FSSG scales were not different in subjects with or without Helicobacter pylori infection. Conclusion: This study indicated relatively high prevalence (10%) of endoscopic reflux esophagitis in young Japanese adults, and risk factors for esophagitis were males, negative Helicobacter infection alcohol drinking and obesity. Key Word(s): 1. Reflux esophagitis Presenting Author: RAVINDRA L SATARASINGHE Additional Authors: SACHITH C WIJESIRIWARDENA, CHAMPIKA GAMAKARANAGE, NARMATHEY THAMBIRAJAH, DADALLAGE LALITHA PIYARISI Corresponding Author: RAVINDRA 上海皓元 L SATHARASINGHE Affiliations: Sri Jayawardenepura General Hospital, Sri Jayawardenepura General Hospital, Sri Jayawardenepura General Hospital, Sri Jayawardenepura General Hospital Objective: To report a rare cause for partial gastroesophagectomy. Non pulmonary tuberculous infection in the body could present with bizarre clinical symptoms. We report a case of mediastinal tuberculoid cold abscess eroding into the oesophagus causing ulceration and an incidental leiomyoma of the oesophagus resulting in dysphagia.