“One-dimensional magnetic nanowires have been introduced into polydimethylsiloxane (PDMS) to form polymer based nanocomposites. In contrast to the conventional nanofillers such as carbon
nanotubes, carbon nanofibers, nanoparticles, and layer-structured materials, these well-defined anisotropic metallic nanowires are highly conductive and have much weaker van der Waals interactions. Moreover, composition modulation can be introduced along the wire axis to achieve multifunctionalities. Incorporation of magnetic segment(s) to the nanowire makes it possible to use external magnetic field to manipulate the distribution and alignment of nanowires when they are suspended in liquids. To characterize the mechanical responses of the nanowire-elastomer composite, an approach using microscale rulers has been
Proteasome inhibitor developed to improve the resolution of strain measurement. Mechanical strengthening effects in PDMS composites with randomly and aligned nickel nanowires have been investigated.”
“The anti-apoptotic protein Mcl-1 is highly expressed in various types of malignant tumors. Overexpression is reported to correlate with poor prognosis and disease progression. We report the expression levels of Mcl-1 in tumor samples of the parotid gland. A retrospective study containing 108 patients was performed. A tissue microarray of six malignancies learn more of the parotid gland and pleomorphic adenoma as control was constructed. Parotid gland tumor samples were immunohistochemically stained for Mcl-1 and expression intensities Ion Channel Ligand Library were assessed. Statistical analysis included correlation to patients’ clinical data and comparison of malignancies to the adenoma.
All malignancies had significantly higher expression of Mcl-1 than the pleomorphic adenomas. The intensity, however, had no significant correlation to overall survival.
Our immunohistochemical findings indicate that parotid gland malignancies produce high levels of Mcl-1 protein. Therefore, Mcl-1 might serve as a predictive co-marker in tumors of the parotid
“SETTING: South Africa currently maintains separate surveillance systems for tuberculosis (TB) and human immunodeficiency virus (HIV). There are future plans for integration of these systems; however, the consistency of information across the existing systems has not previously been assessed.
OBJECTIVE: To determine the completeness and concordance of data in the TB and HIV surveillance systems for TB-HIV co-infected patients.
DESIGN: In a retrospective cohort evaluation of the records of TB-HIV co-infected patients in the Eden District of the Western Cape, data were abstracted from paper-based and electronic TB and HIV surveillance sources. Concordance was measured using Fleiss’ kappa coefficient.